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Allele : Plekhm1<tm1.2Hzhao> pleckstrin homology domain containing, family M (with RUN domain) member 1; targeted mutation 1.2, Haibo Zhao
Primary Identifier  MGI:5888869 Allele Type  Targeted
Attribute String  Null/knockout Gene  Plekhm1
Transmission  Germline Strain of Origin  (129S6/SvEvTac x C57BL/6J)F1
Is Recombinase  false Is Wild Type  false
molecularNote  The targeting vector was designed to insert a loxP site upstream of exon 3 and an FRT-flanked neomycin resistance (neo) cassette, followed by a second loxP site, downstream of exon 3. Germline Flp- and Cre- mediated recombination removed the FRT-flanked neo cassette and exon 3 sequences. Quantitative real-time PCR analysis confirmed the absence of exon 3 genomic DNA in several soft tissues and tibial bone from homozygous mutant mice.
  • mutations:
  • Intragenic deletion
  • synonyms:
  • Plekhm1<->,
  • Plekhm1<->
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

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4 Publication categories

Trail: Allele




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