| First Author | Adamson MC | Year | 1991 |
| Journal | Virology | Volume | 183 |
| Issue | 2 | Pages | 778-81 |
| PubMed ID | 1649508 | Mgi Jnum | J:11338 |
| Mgi Id | MGI:59774 | Doi | 10.1016/0042-6822(91)91010-e |
| Citation | Adamson MC, et al. (1991) The mouse homolog of the Gibbon ape leukemia virus receptor: genetic mapping and a possible receptor function in rodents. Virology 183(2):778-81 |
| abstractText | The mouse homolog of the Gibbon ape leukemia virus (GALV) receptor (Glvr-1) was mapped to mouse Chromosome 2 (Chr 2) by Southern blot analysis of somatic cell hybrids and positioned on this chromosome using an interspecies genetic cross. Mouse Chr 2 also encodes a receptor (Rec-2) for the wild mouse virus M813. To investigate whether Glvr-1 and Rec-2 could be the same gene, we sought evidence for sequence homology between the env- genes of their respective viruses. Southern blot hybridization with GALV-derived env and pol-env probes failed to detect any homology between GALV and M813, but did show that all mouse species tested carry numerous copies of GALV-related sequences. We speculate that a functional receptor for GALV-related viruses was expressed during Mus evolution. |
