First Author | Lieberman LA | Year | 2004 |
Journal | Infect Immun | Volume | 72 |
Issue | 11 | Pages | 6729-32 |
PubMed ID | 15501812 | Mgi Jnum | J:93275 |
Mgi Id | MGI:3056714 | Doi | 10.1128/IAI.72.11.6729-6732.2004 |
Citation | Lieberman LA, et al. (2004) Interleukin-15-deficient mice develop protective immunity to Toxoplasma gondii. Infect Immun 72(11):6729-32 |
abstractText | Previous studies have suggested an important role for interleukin-15 (IL-15) in resistance to and memory for Toxoplasma gondii infection. The studies presented here reveal that IL-15 is not required for infection-induced expansion of NK or CD8+ T cells. Furthermore, IL-15-/- mice develop long-term protective immunity to this pathogen. |