Primary Identifier | IPR017074 | Type | Family |
Short Name | mRNA_cap_enz_bifunc |
description | This entry represents bifunctional mRNA-capping enzymes that exhibit RNA 5'-triphosphatase activity () in the N-terminal region and mRNA guanylyltransferase activity () in the C-terminal region []. These enzymes catalyse the first two steps of cap formation via the following steps:Removing the gamma-phosphate from the 5'-triphosphate end of nascent mRNA to yield a diphosphate end.Followed by the transfer of the gmp moiety of GTP to the 5'-diphosphate terminus. |