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Protein Coding Gene : Prl3c1 prolactin family 3, subfamily c, member 1

Primary Identifier  MGI:1351649 Organism  mouse, laboratory
Chromosome  13 NCBI Gene Number  27372
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.0.0)

Predicted to enable hormone activity and prolactin receptor binding activity. Predicted to be involved in several processes, including female pregnancy; positive regulation of lactation; and positive regulation of receptor signaling pathway via JAK-STAT. Predicted to be located in extracellular region. Predicted to be active in extracellular space. Is expressed in decidua; extraembryonic component; placenta; and uterus stroma. Used to study hyperandrogenism.
PHENOTYPE: Mice homozygous for a knock-out allele exhibit reduced female fertility and a male reproductive tract phenotype that includes enlarged testes and seminal vesicles, increased sperm count, increased serum testosterone and luteinizing hormone levels, and abnormal adult Leydig cell differentiation. [provided by MGI curators]
  • synonyms:
  • prolactin family 3, subfamily c, member 1,
  • PLP I,
  • Prlpj,
  • PLP-J,
  • Prl3c1,
  • prolactin-like protein J,
  • MGI:1861442

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Genome

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0 Canonical

0 CDSs

0 Exons

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2 Involved In Mutations

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0 Transcripts

0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

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Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

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Disease

Mouse features --> Human diseases

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