Primary Identifier | IPR044510 | Type | Family |
Short Name | RIC1-like |
description | This entry represents a group of plant CRIB domain-containing proteins including RIC1-11 (exclude 2 and 4) from Arabidopsis. They belong to the RIC (ROP-interactive CRIB motif-containing protein) family. RIC1 is inactivated by active ROP2 in the lobe-forming regions of pavement cells, which suppresses MT assembly, but promotes fine F-actin assembly and thereby induces outgrowth of the region. In contrast, RIC1 is activated by active ROP6 in the neck-forming regions of pavement cells, and then promotes the assembly of MTs, which limits the expansion of the region and results in the formation of a narrow neck. RIC1 also positively regulates the auxin effect and negatively regulates the ABA effect during root growth and lateral root development [].RIC7 functions as downstream effector of active ROP2 which is involved in the prevention of excessive stomatal opening upon light stimulation []. It is also involved in pollen tube growth regulation through its interaction with ROP1 [].The RIC (ROP-interactive CRIB motif-containing protein) family members act as Rho GTPase (Rop) targets that function in distinct Rop signaling pathways []. RICs interact with multiple ROP GTPases via their conserved CRIB motif, and link ROP proteins to diverse target molecules that bind to their variable domains []. RICs share several consensus amino acid residues upstream of the CRIB motif and a consensus PSWMXDFK block downstream of the CRIB motif. Unlike other group members, members of group V, consisting of RIC4 and RIC2, lack the PSWMXDFK block and contain a relatively long N terminus in front of the CRIB motif and a short C terminus []. |