Primary Identifier | MGI:7660785 | Allele Type | Endonuclease-mediated |
Attribute String | Null/knockout | Gene | Aifm3 |
Strain of Origin | Not Specified | Is Recombinase | false |
Is Wild Type | false |
molecularNote | CRISPR/Cas9 technology targeting the intron 3-exon 4 junction using gRNAs UUCAAUCUUGAGCUCCACUG and GUGCUGCCAGAGAAAGAGCG generated a 9 bp deletion (chr16:17317404 GTCCACAGTG > G), resulting in a splice acceptor deletion and subsequently frameshift mutation. |