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Allele : Aifm3<em1Jgg> apoptosis-inducing factor, mitochondrion-associated 3; endonuclease-mediated mutation 1, Joseph G Gleeson

Primary Identifier  MGI:7660785 Allele Type  Endonuclease-mediated
Attribute String  Null/knockout Gene  Aifm3
Strain of Origin  Not Specified Is Recombinase  false
Is Wild Type  false
molecularNote  CRISPR/Cas9 technology targeting the intron 3-exon 4 junction using gRNAs UUCAAUCUUGAGCUCCACUG and GUGCUGCCAGAGAAAGAGCG generated a 9 bp deletion (chr16:17317404 GTCCACAGTG > G), resulting in a splice acceptor deletion and subsequently frameshift mutation.
  • mutations:
  • Intragenic deletion
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

3 Publication categories

Trail: Allele