First Author | Hynes NE | Year | 2012 |
Journal | Cancer Discov | Volume | 2 |
Issue | 1 | Pages | 19-22 |
PubMed ID | 22585164 | Mgi Jnum | J:193084 |
Mgi Id | MGI:5467501 | Doi | 10.1158/2159-8290.CD-11-0317 |
Citation | Hynes NE, et al. (2012) The 14-3-3sigma tumor suppressor has multiple functions in ErbB2-induced breast cancer. Cancer Discov 2(1):19-22 |
abstractText | Ling and colleagues demonstrated that loss of the conditional 14-3-3sigma allele results in accelerated HER2/ERBB2-driven mammary tumorigenesis and metastasis. This study underscores the role of 14-3-3sigma as a potent tumor suppressor in ERBB2-driven tumor initiation and progression. |