| Primary Identifier | MGI:7560637 | Allele Type | Endonuclease-mediated |
| Gene | Birc2 | Strain of Origin | C57BL/6N |
| Is Recombinase | false | Is Wild Type | false |
| description | This allele was generated at the same time as Birc3em1Haka. |
| molecularNote | CRISPR/Cas9 technology generated a 13-bp deletion leading to a frameshift that shortens the protein by three amino acids introducing a premature stop codon at position 610 (T602LfsTer7). This deletion was generated by simultaneously injecting C57BL/6N zygotes with two sgRNAs targeting Birc2 (5â-TCTGCAGGGGGACAATCAAG-3â) and Birc3 (5â-ATCTGTAGAGGGACCATCAA-3â) and was generated at the same time as the Birc3em1Haka allele. |
