| Type | MGI:General | Description | sperm motility is significantly reduced; mean curvilinear velocity (microns per second) is significantly lower than that in heterozygous controls mean percentage of motile sperm is ~32.8% relative to ~76.7% in heterozygous controls whereas administration of 1 mM ATP alone does not significantly rescue microtubule sliding, a combination of either 4 mM AMP or 4 mM ADP with 1 mM ATP supports partial rescue of microtubule sliding in dyskinetic sperm; however, partial rescue is not observed using 1:1 molar ratios of ATP with either AMP or ADP |
