| Primary Identifier | MGI:3046905 | Allele Type | Gene trapped |
| Attribute String | Null/knockout, Reporter | Gene | Ptk7 |
| Transmission | Germline | Strain of Origin | 129P2/OlaHsd |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | A gene trap vector including a beta-galactosidase and neo was inserted into intron 2. The allele is predicted to result in a null or a severely hypomorphic mutation, with the in-frame fusion of the first 114 amino acids to the transmembrane Beta-gal and neo construct. A transcript with the expected size for the fused RNA was detected in Northern blot of mutant brain lysates, and Western blot showed a peptide of the size of the predicted fusion product instead of the two peptides detected in wild-type brain lysates. |
