| Primary Identifier | MGI:2443902 | Organism | mouse, laboratory |
| Chromosome | 7 | NCBI Gene Number | 338352 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0) Predicted to enable heparin binding activity; identical protein binding activity; and protein kinase C binding activity. Predicted to be involved in several processes, including negative regulation of osteoblast proliferation; positive regulation of bone mineralization; and positive regulation of osteoblast differentiation. Predicted to act upstream of or within cell differentiation. Predicted to be located in nuclear envelope and perinuclear region of cytoplasm. Predicted to be active in cytoplasm and extracellular space. Is expressed in several structures, including basal columns; chondrocranium; tooth; tooth bud; and urinary system. Orthologous to human NELL1 (neural EGFL like 1). PHENOTYPE: Homozygous mice display perinatal lethality, respiratory failure, impaired development of the intervertebral disks, vertebrae and calvarial bones, increased skull length, and abnormal curvature of the spine. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
