| Primary Identifier | MGI:1201690 | Organism | mouse, laboratory |
| Chromosome | 7 | NCBI Gene Number | 17760 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0) Enables microtubule binding activity. Predicted to be involved in several processes, including axonal transport of mitochondrion; dendrite morphogenesis; and positive regulation of axonogenesis. Predicted to be located in several cellular components, including Golgi apparatus; perinuclear region of cytoplasm; and secretory vesicle. Predicted to be active in several cellular components, including Golgi-associated vesicle; cis-Golgi network; and microtubule. Is expressed in cortical plate; cranial ganglion; dorsal root ganglion; and sensory organ. Used to study schizophrenia. Orthologous to human MAP6 (microtubule associated protein 6). PHENOTYPE: Mice homozygous for a targeted null mutation are devoid of cold-stable microtubules, and exhibit impaired synaptic plasticity, associated with severe behavioral abnormalities that are specifically ameliorated by long-term administration of neuroleptics. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
