Primary Identifier | IPR035836 | Type | Domain |
Short Name | ASAP1-like_SH3 |
description | ASAP1 is an Arf GAP that associates with and regulates actin-based structures. It is also involved in actin remodeling affecting cell spreading and cell migration []. ASAP1 contains BAR, PH, Arf GAP, Ank repeats, Proline-rich, E/DLPPKP repeat, and SH3 domains. It binds to focal adhesion kinase (FAK) via its SH3 domain []. The BAR domain of ASAP1 is also critical for its cellular function in regulation of actin-based structures [].This entry includes the SH3 domain of ASAP1. |