Primary Identifier | MGI:7443203 | Allele Type | Endonuclease-mediated |
Attribute String | Modified regulatory region | Gene | Rr273 |
Strain of Origin | (C57BL/6J x DBA/2J)F1 | Is Recombinase | false |
Is Wild Type | false |
molecularNote | The Vsx2 enhancer, part of super-enhancer Rr272, was targeted with sgRNAs (targeting GTTAGACCTAGTCAGAACTC and TACTTCAGACTCTGGCTCCA) using CRISPR/Cas9 technology, resulting in a 789 bp deletion (chr12:84578820-84579608 (GRCm39)). |