| Primary Identifier | MGI:3043381 | Organism | mouse, laboratory |
| Chromosome | 4 | NCBI Gene Number | 242553 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to be involved in negative regulation of actin filament polymerization. Predicted to act upstream of or within negative regulation of stress fiber assembly. Predicted to be located in cytosol and microtubule cytoskeleton. Predicted to be active in cytoplasm and cytoskeleton. Is expressed in extrinsic ocular muscle; lung; metanephros; and ureteric tip. Orthologous to human KANK4 (KN motif and ankyrin repeat domains 4). PHENOTYPE: Homozygous null mice show impaired arteriogenesis of the collateral artery due to decreased endothelial cell proliferation in response to ischemia. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
