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Allele : Spink2<Gt(327A6)Cmhd> serine peptidase inhibitor, Kazal type 2; gene trap 327A6, Centre for Modeling Human Disease

Primary Identifier  MGI:4966113 Allele Type  Gene trapped
Attribute String  Null/knockout, Reporter Gene  Spink2
Transmission  Germline Strain of Origin  (129X1/SvJ x 129S1/Sv)F1-Kitl<+>
Is Recombinase  false Is Wild Type  false
molecularNote  The gene trap inserted upstream of exon 1 and resulted in a transcript containing the gene trap fused to exon 2. A 75% reduction in protein expression was confirmed by western blot analysis. This allele is hypomorphic.
  • mutations:
  • Insertion of gene trap vector
  • synonyms:
  • Spink2<gt>,
  • Spink2<gt>,
  • MGI:3883894
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

4 Publication categories

Trail: Allele