Primary Identifier | MGI:3521576 | Allele Type | Targeted |
Attribute String | Null/knockout | Gene | Hap1 |
Transmission | Germline | Strain of Origin | 129S1/Sv-Oca2<+> Tyr<+> Kitl<+> |
Is Recombinase | false | Is Wild Type | false |
molecularNote | A targeting vector was designed to replace 5 kb of sequence containing the promoter, exon 1 and a portion of intron 1 with a neo cassette placed in opposite orientation of transcription. Northern blot indicated the absence of transcript in mutant neonatal mouse brains. |