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Allele : Il4i1<H46-b> interleukin 4 induced 1; histocompatibility 46, b variant

Primary Identifier  MGI:6197069 Gene  Il4i1
Inheritance Mode  Semidominant Strain of Origin  129/Sv
Is Recombinase  false Is Wild Type  false
molecularNote  This minor histocompatibility antigen, initially identified as being between C57BL/10ScSn and 129/Rr but also found to be between C57BL/6J and 129P3/J, is caused by a single amino acid change at residue 25, which is alanine in C57BL/6J-derived H46-a and methionine for 129-derived H46-b. The 2 nucleotide sequence variations underlying this are G73A and C74T and the core antigenic peptide from each compete similarly for binding Ab. The core antigenic peptide in H46-b is HMFVEAIPELQ.
  • mutations:
  • Nucleotide substitutions
  • synonyms:
  • H46<b>,
  • H46<b>
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

3 Carried By

Trail: Allele

0 Driven By

2 Publication categories

Trail: Allele