First Author | Han HJ | Year | 1996 |
Journal | Cytogenet Cell Genet | Volume | 73 |
Issue | 1-2 | Pages | 137-9 |
PubMed ID | 8646882 | Mgi Jnum | J:33991 |
Mgi Id | MGI:81471 | Doi | 10.1159/000134325 |
Citation | Han HJ, et al. (1996) Isolation and mapping of a human gene (RABL) encoding a small GTP-binding protein homologous to the Ras-related RAB gene. Cytogenet Cell Genet 73(1-2):137-9 |
abstractText | Many subgroups of the RAB gene, a member of the RAS superfamily have been identified. Here we report the isolation and analysis of a cDNA encoding a putative small GTP-binding protein, designated RABL, from a human fetal lung cDNA library. RABL encodes 216 amino acids that are 86% identical to members of the RAB5 subfamily and it shows 94% homology in nucleotide sequence with RAB5C of dog. This gene was expressed ubiquitously in all human tissues examined. By fluorescence in situ hybridization we mapped RABL to chromosome band 17q21.2. |