Primary Identifier | IPR014110 | Type | Family |
Short Name | TraF |
description | This entry includes TraF; a protein that is part of a large group of proteins involved in conjugative transfer of plasmid DNA, specifically in the F-type system. TraF has been predicted to contain a thioredoxin fold and has been shown to be localized to the periplasm []. Unlike the related protein TrbB (), TraF does not contain a conserved pair of cysteines and has been shown not to function as a thiol disulphide isomerase by complementation of an Escherichia coli DsbA defect []. The protein is believed to be involved in pilin assembly []. Even more closely related than TrbB is a clade of genes (), which do contain the CXXC motif, but it is unclear whether these are involved in type-F conjugation systems per se. |