| First Author | Omori Y | Year | 1997 |
| Journal | Cytogenet Cell Genet | Volume | 78 |
| Issue | 3-4 | Pages | 285-8 |
| PubMed ID | 9465904 | Mgi Jnum | J:45384 |
| Mgi Id | MGI:1195356 | Doi | 10.1159/000134673 |
| Citation | Omori Y, et al. (1997) Cloning, expression and mapping of a novel human zinc-finger gene TCF17 homologous to rodent Kid1. Cytogenet Cell Genet 78(3-4):285-8 |
| abstractText | We isolated a novel human zinc-finger gene TCF17 homologous to rat Kid1, a zinc-finger gene of the Kruppel type expressed predominantly in kidney. In the rat this gene seems to be a transcription factor expressed in response to renal injury and ischemia. The 2435-bp human cDNA contained an open reading frame encoding 605 amino acids. The deduced amino acid sequence showed 86.0% and 87.2% identity (91.6% and 92.8% similarity) with the rat Kid1 and mouse Tcf17 respectively. In contrast with rat Kid1, human TCF17 was expressed in all human tissues examined, including kidney. This gene was mapped by FISH to chromosome 5q35.3, where cytogenetic and molecular abnormalities have been reported often in renal cell carcinomas. |
