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Allele : C1qa<tm1d(EUCOMM)Wtsi> complement component 1, q subcomponent, alpha polypeptide; targeted mutation 1d, Wellcome Trust Sanger Institute

Primary Identifier  MGI:6151469 Allele Type  Targeted
Attribute String  Null/knockout Gene  C1qa
Transmission  Germline Strain of Origin  C57BL/6N-A<tm1Brd>
Is Recombinase  false Is Wild Type  false
Project Collection  EUCOMM
molecularNote  The L1L2_Bact_P cassette was inserted at a position on Chromosome 4 upstream of exon 3 of the gene. The cassette is composed of an FRT site followed by lacZ sequence and a loxP site. This first loxP site is followed by neomycin resistance gene under the control of the human beta-actin promoter, SV40 polyA, a second FRT site and a second loxP site. A third loxP site was inserted in the 3' untranslated region of exon 3. Flp-mediated recombination removed the FRT-flanked lacZ and neo cassette. Cre-mediated recombination removed exon 3.
  • mutations:
  • Intragenic deletion,
  • Insertion
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

Trail: Allele

0 Driven By

19 Publication categories

Trail: Allele