Primary Identifier | MGI:2176596 | Allele Type | Targeted |
Attribute String | Null/knockout | Gene | Adcy8 |
Transmission | Germline | Strain of Origin | (129X1/SvJ x 129S1/Sv)F1-Kitl<+> |
Is Recombinase | false | Is Wild Type | false |
molecularNote | A PGK-neomycin resistance cassette replaced a genomic fragment containing exon 1, including the translation initiation site. RT-PCR analysis on RNA derived from hypothalamus or hippocampus of homozygous mice demonstrated that no detectable transcript was produced from this allele. |