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Allele : Adcy8<tm1Ljm> adenylate cyclase 8; targeted mutation 1, Louis J Muglia

Primary Identifier  MGI:2176596 Allele Type  Targeted
Attribute String  Null/knockout Gene  Adcy8
Transmission  Germline Strain of Origin  (129X1/SvJ x 129S1/Sv)F1-Kitl<+>
Is Recombinase  false Is Wild Type  false
molecularNote  A PGK-neomycin resistance cassette replaced a genomic fragment containing exon 1, including the translation initiation site. RT-PCR analysis on RNA derived from hypothalamus or hippocampus of homozygous mice demonstrated that no detectable transcript was produced from this allele.
  • mutations:
  • Intragenic deletion,
  • Insertion
  • synonyms:
  • AC8-,
  • AC8-,
  • AC8 KO,
  • AC8 KO
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

45 Publication categories

Trail: Allele