Primary Identifier | MGI:1914710 | Organism | mouse, laboratory |
Chromosome | 4 | NCBI Gene Number | 67460 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable 2,4-dienoyl-CoA reductase (NADPH) activity; NADPH binding activity; and identical protein binding activity. Involved in positive regulation of cold-induced thermogenesis. Located in mitochondrion. Is expressed in axial skeleton and heart. Orthologous to human DECR1 (2,4-dienoyl-CoA reductase 1). PHENOTYPE: Mice homozygous for a null allele exhibit increased sensitivity to fasting and cold stresses. [provided by MGI curators] |