First Author | Kwong LN | Year | 2013 |
Journal | Cancer Discov | Volume | 3 |
Issue | 12 | Pages | 1339-44 |
PubMed ID | 24327696 | Mgi Jnum | J:208369 |
Mgi Id | MGI:5562982 | Doi | 10.1158/2159-8290.CD-13-0394 |
Citation | Kwong LN, et al. (2013) A systems biology approach to personalizing therapeutic combinations. Cancer Discov 3(12):1339-44 |
abstractText | The identification of evidence-based, efficacious drug combinations for each cancer, among thousands of potential permutations, is a daunting task. In this perspective, we propose a systematic approach to defining such combinations by molecularly benchmarking a drug against a desired state of efficacy using model systems. |