Primary Identifier | MGI:1298227 | Organism | mouse, laboratory |
Chromosome | 1 | NCBI Gene Number | 17219 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Contributes to DNA helicase activity and single-stranded DNA binding activity. Acts upstream of or within DNA unwinding involved in DNA replication. Located in nucleus. Part of MCM complex. Is expressed in several structures, including brain; eye; future brain; genitourinary system; and limb. Orthologous to human MCM6 (minichromosome maintenance complex component 6). PHENOTYPE: Mice homozygous for a gene trapped allele exhibit prenatal lethality. Mice heterozygous for this allele exhibit increased micronulei-containing red blood cells. [provided by MGI curators] |