Primary Identifier | IPR026581 | Type | Family |
Short Name | TCP10_fam |
description | Proteins in this family include T-complex protein 10 and centromere protein J (CENPJ). T-complex is involved in spermatogenesis in mice []. T-complex protein 10A homologue 2 (also known as TCP10L) may be involved in transcriptional regulation and has in vitro transcription inhibition activity []. It acts as a tumour suppressor in hepatocellular carcinoma (HCC) cells []. CENPJ not only inhibits microtubule nucleation from the centrosome, but also depolymerises taxol-stabilised microtubules [, , ]. |