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Protein Domain : T-complex protein 10 family

Primary Identifier  IPR026581 Type  Family
Short Name  TCP10_fam
description  Proteins in this family include T-complex protein 10 and centromere protein J (CENPJ). T-complex is involved in spermatogenesis in mice []. T-complex protein 10A homologue 2 (also known as TCP10L) may be involved in transcriptional regulation and has in vitro transcription inhibition activity []. It acts as a tumour suppressor in hepatocellular carcinoma (HCC) cells []. CENPJ not only inhibits microtubule nucleation from the centrosome, but also depolymerises taxol-stabilised microtubules [, , ].

1 Child Features

0 Parent Features

37 Protein Domain Regions