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Allele : Lrp5<tvrm111B> low density lipoprotein receptor-related protein 5; translational vision research model 111B

Primary Identifier  MGI:5902782 Allele Type  Chemically induced (ENU)
Attribute String  Not Specified Gene  Lrp5
Inheritance Mode  Recessive Strain of Origin  C57BL/6J
Is Recombinase  false Is Wild Type  false
molecularNote  This ENU-induced insertion of a single C into a string of 9 successive cytosines in a highly conserved GC-rich region is predicted to result in the replacement of 39 C-terminal amino acids with 20 novel amino acids, disrupting the last 3 PPPSPxS motifs in the cytoplasmic domain and introducing a premature stop codon.
  • mutations:
  • Nucleotide repeat expansion
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

2 Carried By

Trail: Allele

0 Driven By

3 Publication categories

Trail: Allele