Primary Identifier | MGI:1915958 | Organism | mouse, laboratory |
Chromosome | 15 | NCBI Gene Number | 68708 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables GTP binding activity. Involved in photoreceptor cell morphogenesis. Acts upstream of or within cilium assembly; flagellated sperm motility; and single fertilization. Located in sperm midpiece. Part of intraciliary transport particle B. Is expressed in several structures, including eye; genitourinary system; gut; nervous system; and respiratory system. Orthologous to human RABL2A (RAB, member of RAS oncogene family like 2A) and RABL2B (RAB, member of RAS oncogene family like 2B). PHENOTYPE: Mice homozygous for an ENU-induced allele exhibit male infertility, reduced testis weight, oligospermia, asthenozoospermia and short flagellum. [provided by MGI curators] |