Primary Identifier | MGI:7511610 | Allele Type | Endonuclease-mediated |
Gene | Notch1 | Strain of Origin | C57BL/6J |
Is Recombinase | false | Is Wild Type | false |
molecularNote | CRISRP/Cas9 technology generated an ACC to GTG change at nt19507â19510 resulting in a threonine to valine substitution at amino acid 232 (p.T232V) in exon 4, resulting in a hypermorphic allele. |