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Publication : Lessons learned from the mouse model of short-chain acyl-CoA dehydrogenase deficiency.

First Author  Wood PA Year  1999
Journal  Adv Exp Med Biol Volume  466
Pages  395-402 PubMed ID  10709668
Mgi Jnum  J:61299 Mgi Id  MGI:1354659
Doi  10.1007/0-306-46818-2_46 Citation  Wood PA, et al. (1999) Lessons learned from the mouse model of short-chain acyl-CoA dehydrogenase deficiency. Adv Exp Med Biol 466:395-402
abstractText  The SCAD deficient mouse model has been useful to investigate mechanisms of deficient fatty acid oxidation disease in human patients. This mouse model has been thoroughly characterized and is readily available from the Jackson Laboratory. Using the new technologies of gene-knockout mouse modeling, we envisage developing additional members of the acyl-CoA dehydrogenase family of enzyme deficiencies in mice and furthering our understanding of fatty acid metabolism in health and disease.
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