| Primary Identifier | MGI:3621932 | Allele Type | Targeted |
| Attribute String | Null/knockout | Gene | Mapk11 |
| Transmission | Germline | Strain of Origin | 129P2/OlaHsd |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | An Asp168Ala mutation was inserted into exon 7 via homologous recombination to create a kinase dead mutation. However expression of this allele was unexpectedly low and sequencing detected a single nucleotide polymorphism resulting in a Cys211Arg mutation in the ES cells. No RNA expression is detected in homozygous MEFs or in the cortex of homozygous mice. |
