| First Author | Hirst RG | Year | 1977 |
| Journal | Infect Immun | Volume | 17 |
| Issue | 2 | Pages | 319-24 |
| PubMed ID | 892907 | Mgi Jnum | J:5860 |
| Mgi Id | MGI:54337 | Doi | 10.1128/iai.17.2.319-324.1977 |
| Citation | Hirst RG, et al. (1977) Mechanisms of resistance to Corynebacterium kutscheri in mice. Infect Immun 17(2):319-24 |
| abstractText | Involvement of the mononuclear phagocyte system in the mechanism of resistance to Corynebacterium kutscheri was studied in C57B1/6 and Swiss Lynch mice. A major difference between the two mouse strains was that the phagocytic cells of the livers of C57B1/6 mice destroyed the bacteria with much greater efficiency. There was no evidence of serum factors which might have led to this greater bacterial killing observed in the C57B1/6 mice, and in vivo phagocytosis of C. kutscheri was identical in both mouse strains. Resistance to C. kutscheri could be transferred with spleen and/or bone marrow cells from resistant (Swiss Lynch X C57B1/6) F1 mice to 650-rad irradiated susceptible Swiss Lynch mice. Nonspecific and acquired mechanisms of resistance to C. kutscheri are discussed. |
