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Comment :

Type  MGI:General Description  at E1.0 only 38% of embryos fertilized by homozygous males had reached cell division compared to 62% for wild-type males the difference in fertilization rate decreased from 39% on E1.0 to 15% on E2.0 suggesting both impaired fertilization and a delay in the first cell division at E3.5 only 33% of embryos fertilized by homozygous males had reached the late morula or blastocyst stage compared to 78% for wild-type males