Primary Identifier | MGI:3711720 | Allele Type | Targeted |
Attribute String | Null/knockout | Gene | Psap |
Transmission | Germline | Strain of Origin | 129/SvEv |
Is Recombinase | false | Is Wild Type | false |
molecularNote | The fifth cysteines of saposin C and D were mutated in a targeting vector. The cysteine in exon 11 was changed to a proline to disrupt saposin C, and the cysteine in exon 13 was changed to serine to disrupt saposin D. A floxed neo was included in the vector and was subsequently removed via cre mediated recombination. |