Primary Identifier | MGI:1918639 | Organism | mouse, laboratory |
Chromosome | 2 | NCBI Gene Number | 71389 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.3.0) Predicted to enable several functions, including ATP hydrolysis activity; ATP-dependent chromatin remodeler activity; and transcription coregulator binding activity. Predicted to be involved in cell redox homeostasis; chromatin remodeling; and positive regulation of transcription by RNA polymerase II. Predicted to act upstream of or within chromatin organization. Predicted to be located in nucleoplasm. Predicted to be part of chromatin. Predicted to be active in nucleus. Is expressed in cerebral cortex intermediate zone; cerebral cortex ventricular layer; and cortical plate. Orthologous to human CHD6 (chromodomain helicase DNA binding protein 6). PHENOTYPE: Homozygous null mice display impaired coordination that is not due to muscle weakness or bradykinesia. [provided by MGI curators] |