| Primary Identifier | MGI:6285957 | Allele Type | Chemically induced (ENU) |
| Attribute String | Not Specified | Gene | Il2rb |
| Inheritance Mode | Recessive | Strain of Origin | C57BL/6J |
| Is Recombinase | false | Is Wild Type | false |
| Project Collection | Beutler Mutagenetix |
| description | https://mutagenetix.utsouthwestern.edu/phenotypic/phenotypic_rec.cfm?pk=3753 |
| molecularNote | ENU-induced A to T transversion at base pair 78,481,936 (v38) on chromosome 15, or base pair 29,686 in the GenBank genomic region NC_000081 encoding Il2rb. The mutation corresponds to residue 1,309 in the mRNA sequence NM_008368 within exon 10 of 10 total exons. The mutation results in a tyrosine to phenylalanine substitution at position 387 (Y387F) in the CD122 protein. |
