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Allele : Hint1<tm1b(EUCOMM)Wtsi> histidine triad nucleotide binding protein 1; targeted mutation 1b, Wellcome Trust Sanger Institute

Primary Identifier  MGI:6782387 Allele Type  Targeted
Attribute String  Null/knockout, Reporter Gene  Hint1
Transmission  Germline Strain of Origin  C57BL/6N-A<tm1Brd>
Is Recombinase  false Is Wild Type  false
Project Collection  EUCOMM
molecularNote  The L1L2_Bact_P cassette was inserted at position 54760244 of Chromosome 11 upstream of exon 2 (Build GRCm39). The cassette is composed of an FRT site followed by lacZ sequence and a loxP site. This first loxP site is followed by a neomycin resistance gene under the control of the human beta-actin promoter, SV40 polyA, a second FRT site and a second loxP site. A third loxP site is inserted downstream of the exon 3 at position 54761593. Exons 2 and 3 are thus flanked by loxP sites. Cre mediated recombination without prior flp recombination created a reporter knockout mouse. Further information on targeting strategies used for this and other IKMC alleles can be found at http://www.informatics.jax.org/mgihome/nomen/IKMC_schematics.shtml
  • mutations:
  • Intragenic deletion,
  • Insertion
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1 Feature

Trail: Allele


0 Expresses

0 Mutation Involves


Mouse alleles --> Mammalian phenotypes (MP terms)



1 Carried By

Trail: Allele

4 Publication categories

Trail: Allele