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Allele : E2f1<Tg(Wnt1-cre)2Sor> E2F transcription factor 1; transgene insertion 2, Philippe Soriano

Primary Identifier  MGI:5485027 Allele Type  Transgenic
Attribute String  Null/knockout, Recombinase Gene  E2f1
Strain of Origin  C57BL/6 x C3H Is Recombinase  true
Is Wild Type  false
molecularNote  A transgenic insert containing cre recombinase, under the control of the 1.3 kb 5' promoter and 5.5 kb 3' enhancer of the mouse Wnt1, wingless-related MMTV integration site 1 was injected into fertilized B6C3 hybrid mouse eggs. Founder line 2 inserted into the gene at 154561346-154561603 (Build GRCm38/mm10) resulting in a 257 bp deletion and a 45 Kb inverted segment in exon 5 of the gene. The inversion contains all of exon 5, but deletes 23 Kb including exons 6 and 7. Founder line 2 has a copy number of 1-3.
  • mutations:
  • Insertion,
  • Inversion,
  • Intragenic deletion
  • synonyms:
  • Wnt1-Cre,
  • Wnt1-Cre2,
  • Tg(Wnt1-cre)2Sor,
  • Tg(Wnt1-cre)2Sor,
  • Wnt1-Cre,
  • Wnt1-Cre2
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

5 Carried By

Trail: Allele

1 Driven By

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136 Publication categories

Trail: Allele