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Protein Coding Gene : Agrp agouti related neuropeptide
Primary Identifier  MGI:892013 Organism  mouse, laboratory
Chromosome  8 NCBI Gene Number  11604
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0)

Enables neuropeptide hormone activity. Acts upstream of or within adult feeding behavior and neuropeptide signaling pathway. Predicted to be located in Golgi lumen and neuronal cell body. Predicted to be active in extracellular space. Is expressed in several structures, including adrenal gland; genitourinary system; hypothalamus; lung; and spleen. Human ortholog(s) of this gene implicated in obesity and type 2 diabetes mellitus. Orthologous to human AGRP (agouti related neuropeptide).
PHENOTYPE: Mice homozygous for a null mutation do not exhibit any detectable abnormalities. [provided by MGI curators]
  • synonyms:
  • agouti related transcript,
  • agouti related neuropeptide,
  • agouti related protein,
  • Agrt,
  • Agrp
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Features --> Cross References

Genome

Sequence Feature Displayer

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0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

1 Involved In Mutations

Trail: ProteinCodingGene

0 Strain

0 Transcripts

0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

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0 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

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9 Driver For

Trail: ProteinCodingGene




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