| First Author | Dupree P | Year | 1992 |
| Journal | Gene | Volume | 120 |
| Issue | 2 | Pages | 325-6 |
| PubMed ID | 1398150 | Mgi Jnum | J:40927 |
| Mgi Id | MGI:892646 | Doi | 10.1016/0378-1119(92)90118-9 |
| Citation | Dupree P, et al. (1992) Sequence of a canine cDNA clone encoding a Ran/TC4 GTP-binding protein. Gene 120(2):325-6 |
| abstractText | We report the isolation and characterization of a canine cDNA encoding a 216-amino acid GTP-binding protein of the Ras superfamily. The protein is almost identical to the human TC4 [Drivas et al., Mol. Cell. Biol. 10 (1990) 1793-1798] and Ran [Bischoff and Ponstingl, Proc. Natl. Acad. Sci. USA 88 (1991) 10830-10834; Nature 354 (1991) 80-82] proteins, the latter of which has been found to be involved in cell cycle control. Furthermore, the protein is highly similar to the fission yeast spi1 gene product [Matsumoto and Beach, Cell 66 (1991) 347-360]. The high degree of evolutionary conservation in this protein suggests that it plays a vital role in the eukaryotic cell. |
