| Primary Identifier | MGI:2445229 | Allele Type | Targeted |
| Attribute String | Null/knockout, Reporter | Gene | Atf1 |
| Transmission | Germline | Strain of Origin | 129 |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | Homologous recombination of a construct containing lacZ and neo resulted in the deletion of a portion of exon 3 and all of exons 4 through 7. The targeted region encoded amino acids 200 through 1380, corresponding to the protein kinase A and leucine zipper domains. Protein was undetected in homozygous mutant mice by Western blot analysis of kidney, liver, and testis tissues. Beta-galactosidase staining showed the expression pattern of lacZ to be similar to that of the endogenous gene. |
