First Author | Vigneau S | Year | 2001 |
Journal | Genomics | Volume | 78 |
Issue | 3 | Pages | 206-13 |
PubMed ID | 11735227 | Mgi Jnum | J:73275 |
Mgi Id | MGI:2154833 | Doi | 10.1006/geno.2001.6656 |
Citation | Vigneau S, et al. (2001) Homology between a 173-kb region from mouse chromosome 10, telomeric to the Ifng locus, and human chromosome 12q15. Genomics 78(3):206-13 |
abstractText | We sequenced a 173-kb region of mouse chromosome 10, telomeric to the Ifng locus, and compared it with the human homologous sequence located on chromosome 12q15 using various sequence analysis programs. This region has a low density of genes: one gene was detected in the mouse and the human sequences and a second gene was detected only in the human sequence. The mouse gene and its human orthologue, which are expressed in the immune system at a low level, produce a noncoding mRNA. Nonexpressed sequences show a higher degree of conservation than exons in this genomic region. At least three of these conserved sequences are also conserved in a third mammalian species (sheep or cow). |