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Publication : Homology between a 173-kb region from mouse chromosome 10, telomeric to the Ifng locus, and human chromosome 12q15.

First Author  Vigneau S Year  2001
Journal  Genomics Volume  78
Issue  3 Pages  206-13
PubMed ID  11735227 Mgi Jnum  J:73275
Mgi Id  MGI:2154833 Doi  10.1006/geno.2001.6656
Citation  Vigneau S, et al. (2001) Homology between a 173-kb region from mouse chromosome 10, telomeric to the Ifng locus, and human chromosome 12q15. Genomics 78(3):206-13
abstractText  We sequenced a 173-kb region of mouse chromosome 10, telomeric to the Ifng locus, and compared it with the human homologous sequence located on chromosome 12q15 using various sequence analysis programs. This region has a low density of genes: one gene was detected in the mouse and the human sequences and a second gene was detected only in the human sequence. The mouse gene and its human orthologue, which are expressed in the immune system at a low level, produce a noncoding mRNA. Nonexpressed sequences show a higher degree of conservation than exons in this genomic region. At least three of these conserved sequences are also conserved in a third mammalian species (sheep or cow).
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