Primary Identifier | MGI:5706941 | Allele Type | Targeted |
Attribute String | Null/knockout | Gene | Dusp5 |
Transmission | Germline | Strain of Origin | C57BL/6NTac |
Is Recombinase | false | Is Wild Type | false |
molecularNote | A floxed neo cassette was inserted upstream of exon 1 and a loxP site was inserted downstream of exon 1 via homologous recombination. Cre-mediated recombination removed the neo cassette and exon 1. Western blot analysis confirmed the absence of protein expression in activated CD4+ T cells. |