Primary Identifier | MGI:1349409 | Organism | mouse, laboratory |
Chromosome | 11 | NCBI Gene Number | 26572 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.4.0) Acts upstream of or within in utero embryonic development. Part of COP9 signalosome. Is expressed in several structures, including central nervous system; inner cell mass; reproductive system; skeletal muscle tissue; and urinary system. Orthologous to human COPS3 (COP9 signalosome subunit 3). PHENOTYPE: Mice homozygous for disruptions in this gene display embryonic lethality with defects in developmental patterning and failure of the inner cell mass to proliferate. [provided by MGI curators] |