Primary Identifier | MGI:3707532 | Allele Type | Targeted |
Attribute String | Hypomorph | Gene | Mesp2 |
Transmission | Germline | Strain of Origin | (C57BL/6NCrlj x CBA/JNCrlj)F1 |
Is Recombinase | false | Is Wild Type | false |
molecularNote | The full length protein was expressed, as well as a FLAG tag. A floxed neo included in the vector was subsequently removed via cre mediated recombination. Expression of the knock-in transcript was similar to wild-type in localization, however, expression levels were lower. Likewise, protein expression was lower as well, demonstrating that the allele is a hypomorph. |