| Primary Identifier | MGI:5465281 | Allele Type | Targeted |
| Attribute String | Null/knockout | Gene | Srgap3 |
| Transmission | Germline | Strain of Origin | (129X1/SvJ x 129S1/Sv)F1-Kitl<+> |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | Exon 3 was replaced with a modified one with a premature stop codon. This mutation resembled the breakpoint of the t(3; X)(p25;p11) translocation. Flp-mediated recombination removed the FRT-flanked neo cassette inserted downstream of the modified exon 3. Western blot anlaysis confirmed the absence of protein expression in the adult cortex. |
