|  Help  |  About  |  Contact Us

Allele : Foxh1<tm3.1(Foxh1*)Cvw> forkhead box H1; targeted mutation 3.1, Christopher VE Wright
Primary Identifier  MGI:5705374 Allele Type  Targeted
Attribute String  Inserted expressed sequence, RMCE-ready Gene  Foxh1
Transmission  Germline Strain of Origin  129S6/SvEvTac
Is Recombinase  false Is Wild Type  false
molecularNote  Recombinase mediated cassette exchange with Foxh1tm1Cvw inserted a FRT flanked selection cassette and a Foxh1 locus with a single amino acid mutation in the EH1 domain (FSIKSLLG to ESIKSLLG) and an N-terminal FLAG tag. This mutation disrupts interactions of the EH1 domain with the WD-repeat domain of Groucho related co-repressor proteins. Flp mediated recombination removed the selection cassette.
  • mutations:
  • Nucleotide substitutions,
  • Insertion
  • synonyms:
  • Foxh1<mEH1>,
  • Foxh1<mEH1>
Paste the following link
Quick Links:
SummaryGenomePhenotypeOther
 
Quick Links:
SummaryGenomePhenotypeOther
 
Lists
This Allele isn't in any lists. Upload a list.

1 Feature

Trail: Allele

Genome

1 Expresses

Trail: Allele

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

4 Publication categories

Trail: Allele




MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

Copyright © 2017 by The Jackson Laboratory. All Rights Reserved

© 2002 - 2017 Department of Genetics, University of Cambridge, Downing Street,
Cambridge CB2 3EH, United Kingdom