Primary Identifier | MGI:1913867 | Organism | mouse, laboratory |
Chromosome | 2 | NCBI Gene Number | 66617 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0) Enables protein methyltransferase activity. Predicted to be involved in chromosome segregation and spindle organization. Predicted to act upstream of or within methylation. Predicted to be located in cytosol and nucleoplasm. Predicted to be active in cytoplasm. Orthologous to human NTMT1 (N-terminal Xaa-Pro-Lys N-methyltransferase 1). PHENOTYPE: Mice homozygous for a knock-out allele exhibit preweaning lethality and premature death associated with premature aging, decreased body size and weight, skin thinning, liver degeneration, increased sensitivity to oxidative stress and female infertility. [provided by MGI curators] |