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Protein Coding Gene : Ntmt1 N-terminal Xaa-Pro-Lys N-methyltransferase 1

Primary Identifier  MGI:1913867 Organism  mouse, laboratory
Chromosome  2 NCBI Gene Number  66617
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0)

Enables protein methyltransferase activity. Predicted to be involved in chromosome segregation and spindle organization. Predicted to act upstream of or within methylation. Predicted to be located in cytosol and nucleoplasm. Predicted to be active in cytoplasm. Orthologous to human NTMT1 (N-terminal Xaa-Pro-Lys N-methyltransferase 1).
PHENOTYPE: Mice homozygous for a knock-out allele exhibit preweaning lethality and premature death associated with premature aging, decreased body size and weight, skin thinning, liver degeneration, increased sensitivity to oxidative stress and female infertility. [provided by MGI curators]
  • synonyms:
  • Mettl11a,
  • expressed sequence AL033331,
  • methyltransferase like 11A,
  • AL033332,
  • Ntmt1,
  • RIKEN cDNA 2610205E22 gene,
  • expressed sequence AL033332,
  • 2610205E22Rik,
  • N-terminal Xaa-Pro-Lys N-methyltransferase 1,
  • AL033331,
  • MGI:2145326,
  • MGI:2139140

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Genome

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Canonical gene --> Transcripts in specific strains.

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